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Upon release, Nrf2 translocates to the nucleus and binds to the antioxidant response element (ARE) located in the promoter of genes coding for antioxidant/detoxifying enzymes and scavengers

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One of the most extensively studied and widely used preparations is Triphala , a synergistic blend of three fruits Emblica officinalis (Amla), Terminalia chebula (Haritaki), and Terminalia bellirica (Bibhitaki)

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Researchers isolated this specific fragment because it demonstrated the most potent biological activity among all the fragments tested

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