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Administration: Self-administered subcutaneous injection, typically once daily before bedtime (to align with natural GH secretion patterns)

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However, in meta-analysis of studies of patients with painful DPN, pregabalin was more effective than placebo in improving neuropathic pain associated with DPN (change in least squares [LSs] mean change in mean pain score: 0.56 to 1.26) [34-36]

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