[12] Glutathione synthetase stays true to this rule, in that it uses the energy generated by ATP
Strategies that deplete GSH, such as using inhibitors like BSO which is inhibitor of -glutamylcysteine synthetase (-GCS) , the rate-limiting enzyme in glutathione (GSH) synthesis or by combining prodrug activation with GSH depletion in nanosystems, have shown promise in overcoming MDR and improving chemotherapy effectiveness [72]
Vui lng tham vn kin ca cc chuyn gia/ bc s chuyn khoa trc khi s dng.
Oxidative stress and diabetic retinopathy: development and treatment
Biomed Pharmacother 89:11961206 El Morsy E, Ahmed M (2020) Protective effects of lycopene on hippocampal neurotoxicity and memory impairment induced by bisphenol A in rats
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