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N Engl J Med (2017) 377(1):1327

The healthy adult without ingesting carnosine excreted 24 mol carnosine in 5 h (Gardner et al

What are the risks or unknowns

Moreover, proteins such as EI24 and SIGMAR1 at MAMs stabilize the IP3R-VDAC1-GRP75 complex, thereby regulating mitochondrial autophagic flux and maintaining membrane contact integrity [92, 104, 105]