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In a model of intestinal infection with the parasite Heligmosomoides polygyrus, ChoK inhibition diminished peritoneal macrophage and B-1 lymphocyte frequency, causing compromised immunity against the parasite (67)
S.ChenL.WangD
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doi:10.1038/s41374-018-0091-y 58
The accumulation of mucus provides a breeding ground for chronic bacterial colonization and infection [3]
Concurrently, drug development efforts will benefit from atomic-resolution insights into competitive antagonism, allosteric modulation, and ion channel block
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