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A practical framework looks like this

PHQ-9 had reached 18moderately severe depressionand Hamilton Depression Rating Scale 17 items (HDRS-17) was 22, meeting DSM-5 criteria for a moderate-to-severe major depressive episode

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This left 40 genes for GO:0006749, 781 genes for GO:0005739, and 700 genes for GO:0022857 annotated based on experimental evidence to create the final list of positive class genes for the classifier models

IU conversions (optional): for peptides with defined International Unit conversions per mg

the color may vary from shades of dark brown to black The macules may be single or multiple