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With appropriate clinical trials, this gastric pentadecapeptide may ultimately provide clinically valuable applications for conditions currently lacking optimal treatment options

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Qiu et al., 2021)

Overall, dysregulation of apoptosis in HT reflects both enhanced activation of extrinsic and intrinsic death pathways and suppression of survival signals, ultimately leading to irreversible thyroid tissue loss

doi: 10.1074/jbc.C200256200 91 PiscioneMMazzoneMDi MarcantonioMCMuraroRMincioneG

If approved, this would become the first oral GLP-1 treatment for obesity, expanding options for patients seeking more individualized therapies