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FIGURE 2 3 Clinical applications of GLP-1RAs: comprehensive protection through multi-disease risk reduction 3.1 Cardiovascular protection GLP-1RAs confer substantial cardiovascular benefits that extend beyond glycemic control, primarily by reducing the incidence of major adverse cardiovascular events (MACE)

Acknowledgements We would like to express our sincere thanks to the Real Federacin Hpica Espaola and the Spanish riders for their kind cooperation

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39 Other novel medical approaches There are several other promising medical approaches for the management of obesity

At ~33.3 mg/mL, 1 unit 0.333 mg

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