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However, their efficacy is linked to the need of a minimum intake of caffeine of 3 mg/kg (Jimnez et al., 2021), considered the optimal dose for the ergogenic effects (Guest et al., 2021)

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Ongoing support matters

2d) revealed constitutive induction of CYP2E1 (1.8-fold) and ALDH1A1 (1.4-fold) at both protein and enzymatic activity levels in KO livers relative to WT livers (Fig

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