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2023;35:316331.e6

Description 5-Amino-1MQ Overview (5-amino-1-methylquinolinium), a structural analogue of methylquinolinium, is a small-molecule inhibitor of the cytosolic enzyme nicotinamide N-methyltransferase (NNMT)

Therefore, to identify the role of NF-B and the regulative mechanism between GPX1 and NF-B in SGNs damage induced by peroxynitrite, we measured the NF-B pathway in SGNs after peroxynitrite administration with GPX1 upregulation or deficiency (Figure 8A)

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