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Results Among 1,354 subjects (median age at baseline 49.8 [interquartile range, IQR 40.257.3]) years, 65.2% male, 16.1% hepatitis B e antigen (HBeAg)-positive, 28.6% cirrhotic), baseline median HBV RNA was 3.68 (IQR 2.425.19) log U/mL

Keep the vial upright and allow it to return to room temperature before opening