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Aug 2013;125:40-9

Benefits include skin radiance, liver support, and immune function

Commonly reported side effects include: Gastrointestinal discomfort Allergic reactions Skin rashes Intravenous administration carries additional risks, such as infection, air embolism, or severe allergic reactions

GLP-1 M act through a G protein coupled receptor (GPCR) that couples to Gs

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Switch from tirzepatide to semaglutide when Injection site reactions are persistent and bothersome, since semaglutide has dramatically lower injection site reaction rates