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It was shown that 8 weeks of swimming exercise significantly upregulated Drp1, OPA1, and Mfn2 expression, restored hepatic mitochondrial fusion/fission homeostasis, and upregulated P-AMPK/AMPK, SIRT1, and PGC-1 and their target genes NRF1, NRF2, and TFAM expression

Curcumin-induced fibroblast apoptosis and in vitro wound contraction are regulated by antioxidants and heme oxygenase: implications for scar formation

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The person of skill in the art having regard to the teachings herein will be able to select a suitable administration to suit a particular subject and/or particular therapeutic application