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The study medicines will be in a pen, and must be injected with a needle in the thigh A Research Study of How Overdosing of a New Once Weekly Medicine NNC0148-0287 C (Insulin 287) Influences the Blood Sugar Level in People With Type 2 Diabetes Intervention 1 Intervention 2 Not provided Anticipated Start Date Not provided Actual Start Date 2019-05-07 Anticipated Date of Last Follow-up 2023-09-01 Estimated Primary Completion Date Not provided Estimated Completion Date Not provided Actual Primary Completion Date 2021-09-27 Actual Completion Date 2021-09-27 Age Cohort Genders Accepts pregnant individuals Unspecified Accepts lactating individuals Unspecified Accepts healthy individuals No Inclusion Criteria: * Male or female, aged between 18 and 72 years (both inclusive) at the time of signing informed consent
Kinetic properties of Na+/Ca2+ exchange in basolateral plasma membranes of rat small intestine
In clinical trials of SGLT2 inhibitors in type 2 diabetes, discontinuation rates among those receiving active treatment have been less variable, ranging from 21% during a median follow-up time of 50 months in the DECLARE-TIMI 58 trial of dapagliflozin to 29% during a mean follow-up time of 43 months in the CANVAS trial of canagliflozin [14,15,16,17,18]