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2008;9:S3 Ballesteros-lvarez J, Andersen JK

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These drugs alter insulin signaling, digestion, and appetite suppression by slowing gastric emptying and changing how quickly food moves through the gastrointestinal tract

This persistent state, referred to as anabolic-steroidinduced hypogonadism (ASIH), has been attributed to prolonged suppression of hypothalamic GnRH signalling, desensitisation of pituitary gonadotropes, and potential structural or functional impairment of Leydig cells (79)