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AOD-9604 vs GLP-2 T GLP-2 T (tirzepatide) extends the GLP-1 S mechanism further by co-activating GIP receptors alongside GLP-1, producing a broader incretin effect and generally stronger weight-loss outcomes in published research than single-pathway GLP-1 agonists

The trial proceeded without reported toxicity, and no lethal dose threshold (LD1) was ever established in subsequent safety testing meaning researchers administering the compound could not find a dose that caused death in even 1% of test subjects across the animal model safety work that preceded and followed the human study

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