Its important to remember that medication is just one tool, and the best results come when combined with lifestyle changes
Role of GLP-1 Receptor Agonists for Weight Loss Role of GLP-1 Receptor Agonists for Weight Loss This Harvard Medical School Continuing Education video examines these key questions: What role do GLP1 receptor agonists
Cortisone injections have become less in vogue medically due to their harmful side effects, including loss of muscle tissue, damage to ligaments and tendons, and bone loss
In addition, combining GLP-1R agonists with other peptide agonists or small-molecule therapeutics, including fibroblast growth factor 21 (FGF21), the farnesoid X receptor (FXR) agonist cilofexor with/without the acetyl coenzyme A carboxylase inhibitor firsocostat, a long-acting amylin agonist, cannabinoid receptor antagonists and sodium-glucose cotransporter 2 inhibitors (SGLT-2i), is currently being explored and may lead to additional improvements in NASH features vs GLP-1R agonists therapy alone [79,80,81,82,83]
Semaglutide (Wegovy) recently became the first GLP-1 approved by the FDA to treat adults with MASH with moderate-to-advanced fibrosis, based on the phase 3 ESSENCE trial
Link Fava, M., et al
