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STEP 5 Trial After 2 years, people still kept the weight offaround 15.2% weight loss, and over 60% lost at least 10% of their starting weight

For diabetes treatment, NICE recommends continuing GLP-1 therapy only if HbA1c has fallen by at least 11 mmol/mol (1%) and weight has reduced by at least 3% after approximately 6 months, unless there are individual clinical reasons to continue

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Injection timing and the starting dose When you inject matters almost as much as how much you inject, especially during the starting dose period when your body is still calibrating to triple receptor activation

Additionally, their overall health might decrease unless they incorporate nutrient-dense whole foods that provide other vitamins, minerals, and essential fatty acids, all of which increase GLP-1 naturally