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At UAB, scientists are working to understand not just that these medications work, but how they work: how they act in the brain, how they affect multiple organs at once, why some patients respond better than others and what next-generation versions of these drugs might look like

injections of 200 nmol kg 1 MK-801 (n = 8 mice and n = 4 cages), 600 nmol kg 1 MK-801 (n = 7 mice and n = 4 cages) or vehicle (isotonic saline, n = 7 mice and n = 4 cages) for 7 days

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