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Mechanistically, our analysis implicated a dysregulated sphingolipid pathway in the DCI brain, characterized by the upregulation of the transporter ATP-binding cassette transporter A2 (ABCA2) and the enzymes sphingosine-1-phosphate phosphatase 1 (SGPP1) and ceramide synthase 2 (CERS2)

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NIH StatPearls identifies UTIs as a direct complication of dehydration in pregnant women, creating a cycle where one preventable problem feeds into another