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Elevation in serum leptin level was also observed in these GFAT overexpressing mice

Samples were prepared as described inthe Measurement of protein ADP-ribosylation section, and Western blotting was performed according to the methods described in the Measurement of ADP-ribosylation in Cell culture measurements section, using anti-OXPHOS (ab110413

An enzyme defect results in the premature breakdown of red blood cells

No samples or data points were excluded from the analysis and all representative images were selected on the basis of reproducibility across independent experiments

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Orlistat and MySimba are one of two oral medications currently NHS-licensed for obesity, but it works differently and produces far lower average weight loss (around 35%)