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These medications are broken down into smaller peptides and amino acids throughout the body, with minimal renal or hepatic (liver) involvement

The medicine can: slow stomach emptying reduce hunger signals change insulin and blood sugar responses Because food moves slower, gas and acid can build up

Both medications are effective for weight loss, though some studies suggest Mounjaro may lead to slightly greater weight reduction

One study showed that injections of semaglutide (the active ingredient in Wegovy), which is administered for diabetes or weight loss in the skin of the abdomen, thigh or upper arm, produced little to no injectionsite pain

However, not all of them register with the FDA

For the average patient losing 28% of body weight with parallel improvements in blood pressure, lipids, and metabolic health, the net cardiovascular picture is strongly positive