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The proportion of patients with PCOS who were prescribed semaglutide or tirzepatide increased from 2.4% in 2021 to 17.6% in 2025, representing a 637.5% relative increase

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They also noted that both gluten and soy protein similarly increased GLP-1 secretion

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They should assess adherence, optimize dosing, and consider combination therapy or alternative medications

The diverse approaches regarding the use of semaglutide for weight reduction highlight the necessity to guide physicians and standardize the long-term treatment regimen in anti-obesity medicine