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Pterostilbene prophylactic significantly attenuated airway hyperresponsiveness and dose dependently inhibited CD4+IL-4+T cells with no effect on lymph node CD4+IL-17A+or CD4+IFN-+T cells [207]

This work was supported by the Burroughs Wellcome Fund Vanderbilt SCRIPS Faculty Scholar Award (PI: Naira Baregamian) and the National Cancer Institute/Vanderbilt-Ingram Cancer Center Multi-Tier Developmental Support Grant (P30CA068485) (PI: Naira Baregamian)

doi: 10.1038/nrdp.2017.71 98 HarrisE

FIGURE 3 Anabolic signaling pathways after acute infusion of oIGF-1 Phosphorylation of Akt (Ser 473) and Erk 1/2 (Thr 202/Tyr 204) (Figure 4) increased by 40-fold and 16-fold, respectively, in skeletal muscle from 0 to 15 min of infusion of oIGF-1 at 220 g h 1 compared to animals that received a saline infusion

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Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis