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These transcriptomic alterations suggest that hypoxia is associated with changes in oxygen sensing and metabolic adaptation in USCs, while the functional relevance of these changes requires further validation

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F., Chen, H., Shi, P

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465 From a more novel perspective, the findings that intralesional oncolytic herpes virus treatment enhances anticancer immune responses in immunosuppressive tumor microenvironments provide a biological rationale for the use of this oncolytic modality in cancers that are otherwise unresponsive to immunotherapy