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Notably, the direction of lipolytic modulation may depend on the metabolic context and experimental setting: in insulin-resistant states, semaglutide can improve insulin-mediated suppression of pathological basal lipolysis, while in mechanistic in vitro systems it may enhance stimulated lipid mobilization coupled to increased fatty acid oxidation and downstream metabolic remodeling

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A simple log becomes valuable at the 4-week mark for assessing whether the protocol is working

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Intermittent fasting, Paleolithic, or Mediterranean diets in the real world: exploratory secondary analyses of a weight-loss trial that included choice of diet and exercise

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A systematic review of the evidence for non-surgical weight management for adults with severe obesity: what is cost effective and what are the implications for the design of health services

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