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For tirzepatide, the same logic applies, but note whether taking tirzepatide early could be causing increased side effects
12-14 As many patients with T2DM are overweight or obese, a drug that can help patients achieve any amount of weight loss is often welcomed by patients and physicians alike
Valence specificity If GLP-1 RAs attenuate neural responses to both appetitive and aversive stimuli, this pattern could indicate a generalized dampening of emotional reactivity
For a 180-pound person (approximately 82 kg), this is 98 to 131 grams of protein per day
Compounded drugs typically consist of medications that have been mixed by a licensed pharmacist tailored to an individual patients needs
Key Insight: The contribution to total spend on GLP-1s for members with obesity without a diabetes diagnosis has grown significantly, now constituting almost 16.5% of spend on these drugs compared to 11% in 2022 and just 4% in 2020
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