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GLP-1: Natures Ozempic

Septerna Sector: GPC Septerna R-targeted oral small molecule drug discovery, including GLP-1, GIP, and glucagon receptors HQ: South San Francisco, CA Year Founded: 2019 (under the name GPCR NewCo, Inc.)

2033 (USD BILLION) FIGURE 13 GLP-1 AGONISTS MARKET, BY ROUTE OF ADMINISTRATION, 2025 VS

For someone weighing 100kg, thats 15-25kg, significantly more than the 5-10% typically achieved with diet and exercise alone

GLP-1 medications such as Wegovy and Ozempic have emerged as treatment options for those with a long history of weight loss attempts, yet no long-term success in this area

The FDA approved Foundayo for two primary indications: Chronic weight management: In adults with obesity (BMI 30) or overweight (BMI 27) with at least one weight-related comorbidity such as hypertension, type 2 diabetes, or high cholesterol