The concerns that arose in the meta-analysis caused a desire to study this topic deeper, she says, adding that the Food and Drug Administration (FDA) is currently investigating several safety concerns with semaglutide and has added blood clots to the investigation
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Tahara Y, Hirota M, Shima K, et al
Anti-inflammatory mechanisms may play a role here, as chronic inflammation contributes to glomerular injury and tubulointerstitial fibrosis
Proc Am Assoc Cancer Res 43:662, 2002
As cellular dysfunction accumulates, cells are either killed or become non-functional in a process known as senescence