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No direct head-to-head trial has been conducted, so these comparisons are drawn from separate trials with different populations and durations

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Gallbladder-related symptoms: Sudden severe pain in the upper right abdomen Pain between shoulder blades Nausea with right upper quadrant tenderness Semaglutide increases gallstone risk, and symptoms may require imaging and possible surgical intervention

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This review consolidates the current understanding of these individual interventions and highlights the promising, yet under-explored, potential of their combined application in CRC management

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