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Why Cycling Matters Receptor desensitization occurs when constant peptide exposure downregulates receptor sensitivity

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This sleep dysfunction likely both results from and contributes to other symptoms, creating a vicious cycle where poor sleep worsens pain sensitivity, which further disrupts sleep

[DOI] [PubMed] [Google Scholar] 285.Petrovic I., Dobric I., Drvis P., Shejbal D., Brcic L., Blagaic A.B., Batelja L., Kokic N., Tonkic A., Mise S., et al