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The Drug Controller General of India (DCGI) has recently scrutinized this situation, and citing lack of therapeutic justification, banned 344 such FDCs (27 of which were metformin-based FDCs)

It is not a replacement for prescribed GLP-1 receptor agonists

Inform your healthcare team about all medications, including over-the-counter products

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Contact your healthcare provider if you experience new or worsening swelling, rapid weight gain, or reduced urine output while taking tirzepatide

Let me walk you through what the research actually shows, what I see in practice, and just as importantly where the limits and cautions are