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However, these are averages

The production of inflammatory cytokines causes microglial activation which could activate NF-B leading to more production of cytokines such as IL-1 and TNF- causing a strong inflammatory response, disrupting neuronal function, and finally, neuronal death

Common adverse effects include nausea, diarrhea, decreased appetite, vomiting, and constipation, which are generally mild to moderate and tend to diminish over time

However, these effects were considered not to be clinically relevant

At the highest doses, more than 90% of participants achieved normalisation of liver fat findings of significant interest to researchers working in hepatology and fatty liver disease

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