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doi: 10.1038/ejcn.2012.126 356 TangJWeiYPiCZhengWZuoYShiPet al

Clonidine works through the brain and is often reserved for resistant hypertension or withdrawal-related symptoms, while propranolol acts on the heart and is commonly chosen when blood pressure control is needed alongside migraine prevention, anxiety symptoms, or heart conditions

There were no significant correlations between baseline Hcy levels and hippocampal atrophy on MRI estimated by z-scores ( p = 0.521, Rs = 0.124) (Figure 3A)

10.1016/j.jns.2008.08.021

Water soluble vitamins, like B12, can be tolerated at higher doses without adverse effects upon the body, and the National Academy of Medicine has not established an upper limit of Vitamin B12 intake