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4.3 Ferroptosis and inflammatory bowel disease Inflammatory bowel disease (IBD), including Crohns disease (CD) and ulcerative colitis (UC), is a chronic and progressive disorder with recurrent episodes (134, 135)

Additionally, these modifications may induce significant toxicity by triggering immune responses 46,47

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Oxygen-ozone (OO) therapy, an intervention that activates NRF2, increases SOD, catalase, and HO-1, while suppressing pro-inflammatory cytokines (IL-6, TNF-, IL-1) (33)

As the body's main endogenous antioxidant, Glutathione can support healthy immune function and can neutralize a broad spectrum of free radicals.*Immediate Effect