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The operon is regulated by the per- and polysulfide-sensing repressor, CstR, which binds to the operator-promoter binding site and represses transcription when its two cysteine residues are in the reduced state 23, 24

Small-molecule compounds, including RAS-selective lethal 3 (RSL3) and erastin, promote ferroptosis, whereas proteins such as liproxstatin-1 (Lip-1), ferrostatin-1 (Fer-1), and the iron chelator deferoxamine (DFO) exert opposite effects (69)

doi: 10.1107/S1744309111056028 269 SamarasingheR.TailorP.TamuraT.KaishoT.AkiraS.OzatoK

Storing the compound in a desiccated and temperature-controlled environment helps maintain its integrity for precise chemical synthesis

Tolerance (being able to "hold one's liquor") hampers alcohol's positive effects by reducing the initial stimulant qualities ( yellow line )

a research chemical is not intended for human or veterinary use