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Thus, the combined use of SGLT2i/DPP4i agents (either separately or as a FDC) not only provides medications that complement each other well, but also targets at least six of the eight components in the ominous octet [20]

As Novos patent expires, GLP-1 generics go global Cheaper options may grant many more patients worldwide access to GLP-1s

When delivered as part of a GLP-1 medical program under physician-supervised care, the therapy has a strong safety profile

Constipation and diarrhea both appear in patient reports, sometimes alternating in the same patient across different weeks

10.1016/j.eclinm.2024.102782 6

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