For adults with T2DM and chronic kidney disease to decrease the likelihood of sustained drop in estimated glomerular filtration rate (eGFR), transition to end-stage renal disease, and CV death
Understanding this progression helps patients stay engaged during the early weeks when internal changes are happening even if the scale has not shifted yet
However, alongside these cardiovascular benefits, clinical trials and real-world observations have consistently noted a modest increase in resting heart rate among patients taking GLP-1 receptor agonists
Several recent reviews summarize the main features of UHPH (Zamora and Guamis, 2015
Renal function: NSAIDs can impair kidney function, particularly in patients with pre-existing renal impairment, dehydration, or those taking other nephrotoxic medications
Natural products as anti-glycation agents: possible therapeutic potential for diabetic complications