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The liver is both the primary site of glutathione synthesis and the organ most dependent on it GSH is essential for phase II conjugation reactions that neutralise toxins, drug metabolites, and alcohol breakdown products (acetaldehyde)

These interactions may affect drug efficacy and increase the risk of adverse effects like hyperkalemia, which may cause symptoms such as muscle weakness or an irregular heartbeat

They have not yet been approved for this purpose

Common side effects of GLP-1/GIP include nausea, abdominal pain, dizziness, bloating, and belching

Kanisawa and Suzuki 1978)