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Int J Biol Sci (2021) 17(8):205068

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By stimulating both the GHRH-R and GHS-R1a pathways simultaneously, researchers have observed synergistic GH elevation while maintaining physiological pulsatile release patterns

Locally increased GLP-1 levels might exert paracrine functions on IEL (50) and afferent neurons, impacting mucosal immune responses and feeding patterns, respectively

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