Neu5Gc, a sialic acid derivative, can promote tumor growth and spread by binding to receptors on tumor cells, thus driving tumor development and metastasis
they can consider peptides, but those are handled on an as-needed, case-by-case basis
Dobutamine is a synthetic, direct-acting catecholamine that primarily stimulates -adrenergic receptors to enhance myocardial contractility and increase cardiac output
BPC-157 (Body Protection Compound 157) is a synthetic 15-amino-acid peptide derived from a protein found in human gastric juice
[3] Whether supraphysiological thiol levels compete for those transporters is unknown
A subsequent study identified the compound N-(4-(2-(4-(trifluoromethyl)phenyl)thiazol-4-yl)phenyl)acetamide as a notable SARM1 inhibitor, which demonstrated significant efficacy in a mouse model of CIPN (Fig