In addition, it also helps block the deposition of fats in visceral and peripheral organs
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Thus, production and consumption of NADPH inside the cells should be coordinated to maintain NADPH homeostasis
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In addition, genetic damage and neoplastic transformation have been demonstrated in cells co-cultured in vitro with activated phagocytes [149] and the genotoxic effects observed include formation of DNA strand breaks [151], sister chromatid exchange [154] and mutations [155]
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