Lilly is studying retatrutide in several Phase 3 clinical trials to evaluate its potential efficacy and safety in obesity and overweight with at least one weight-related medical problem, type 2 diabetes, knee osteoarthritis, moderate-to-severe obstructive sleep apnea, chronic low back pain, cardiovascular and renal outcomes and metabolic dysfunction-associated steatotic liver disease
Pricing and regulatory status may change after publication
Phase 3 trials with longer duration will provide clearer answers
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By harnessing the power of a GLP-1, GIP, and glucagon receptor agonist simultaneously, this medication is being studied for effects on appetite, metabolic signaling, and energy balance
In the trial, 930 adults with type 2 diabetes were randomly assigned to receive weekly retatrutide or placebo