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Several studies have explored the utilization of RWD in conducting clinical trials 1,2,3,4 , providing external control groups for single-arm studies 5,6 , and complementing the control group in randomized controlled trials (RCTs) 7,8,9

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Data from the cardiovascular outcome trial (CVOT) SUSTAIN 6 shows that: In patients with high-risk cardiovascular (CV) type 2 diabetes, when combined with standard care Compared to placebo, Ozempic statistically reduced the risk of the MACE composite endpoint by 26%