In addition, KG is a cofactor for the Fe(II)/2-oxoglutarate-dependent dioxygenases (OGDD), including Jumonji-domain (JMJC)-containing histone demethylases, ten-eleven translocation (TET) DNA demethylases and hypoxia-inducible factors (HIF)-prolyl hydroxylases (PHD) essential for HIF-hydroxylation and consequent degradation [70]
Pair with vitamin C: Taking glutathione with liposomal vitamin C may help recycle and stabilise it, supporting antioxidant benefits longer
Carbohydrates cause an increase in insulin levels
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Serious side effects are uncommon but worth discussing with your provider before starting, particularly if you have a history of thyroid conditions, pancreatitis, or gallbladder issues
Serious reactions are rare