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SGLT2 inhibitors were administered for a median of 21 weeks, and 12 patients were diagnosed with severe OSA

We believe that one of the important mechanisms underlying this effect is likely reduction of inflammation in the fatty tissue around the heart, which we know is an important driver of arrhythmias and other unwanted cardiac outcomes. Bilchick plans to continue investigating these inflammatory mechanisms in collaboration with UVA immunology researcher Coleen McNamara, UVA MRI physicist Frederick Epstein (who developed an MRI method to characterize fatty tissue surrounding the heart), and UVA Director of Cardiac Imaging Amit Patel

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ADA 2026: TRANSCEND-T2D-1: Retatrutide Demonstrates Robust Reductions in HbA1c and Body Weight as Monotherapy in Type 2 Diabetes The phase 3 TRANSCEND-T2D-1 trial evaluated the triple GIP, GLP-1, and glucagon receptor agonist in adults with type 2 diabetes inadequately controlled with diet and exercise alone