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Enhanced lipid peroxidation upon GPX4 deletion (GPX4 Mye/ ) was shown to increase the expression of caspase 11 and N-GSDMD in response to LPS transfection and E-coli infection [12]

Braun M, Wassmer G, Klotz T, Reifenrath B, Mathers M, Engelmann U

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However, nanocarriers such as polymeric micelles (PEG-PE) that transform antigenic peptides conformation to facilitate cytosolic delivery could be reliably used for LN targeting, APC uptake and antigen cross presentation 75

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