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Phase 3 trial protocols allow dose reduction at lower BMI levels rather than stopping treatment

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For Foundayo, the most frequently reported side effects were mild to moderate and also gastrointestinal in nature, including nausea, constipation, diarrhea, vomiting, indigestion and stomach pain

Dehydration worsens nausea and can cause headaches that amplify the perceived side effect burden

In comparison of food intake during an ad libitum buffet meal, treatment with pramlintide resulted in an approximately 200 calorie decrease in food intake compared to placebo administration (430)

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