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[5.] Activation of this receptor has been linked in research models to Gq/G11-mediated phospholipase C signaling, inositol trisphosphate production, and intracellular calcium mobilization

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119 In addition, higher blood levels of lycopene and other carotenoids have been correlated with less sperm DNA fragmentation

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Wright JW, Kawas LH, Harding JW. The development of small molecule angiotensin IV analogs to treat Alzheimer's and Parkinson's diseases. Prog Neurobiol. 2015 Feb;125:26-46. doi: 10.1016/j.pneurobio.2014.11.004. Review. PubMed PMID: 25455861