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With the confirmed changes taking effect soon, both patients and healthcare providers are encouraged to plan ahead to avoid any interruptions to treatment.

Combining both medications addresses blood sugar control from multiple angles metformin reduces liver glucose production while Ozempic promotes insulin secretion and suppresses appetite

Instructing the patient to administer the evening NPH insulin dose at bedtime rather than before dinner helps prevent insulin waning and ensures better glycemic control upon waking

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Treatment duration matters significantlyexpect to use Ozempic for 12-18 months minimum, potentially longer for maintenance, making total cost a crucial consideration